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The principle of nucleic acids extraction firstly guarantees the integrity of the primary structure of nucleic acid, and secondly eliminates the contamination of other molecules. When extracting, attention should be paid to shorten the extraction time, reduce the degradation of nucleic acid by chemical and physical factors, mechanical shearing force and high temperature, and prevent […]
Nucleic acid is an important carrier of genetic information and an important biological information molecule. It plays a key role in the process of people’s biological research. At present, there are many methods for isolation and purification of nucleic acids . The most commonly used is (iso)guanidine thiocyanate What is the one-step method of phenol-chloroform, […]
With the outbreak of the new coronavirus, although it has been brought under control, everyone still cannot take it lightly. Everyone should know that all suspected cases and patients with fever must undergo nucleic acid testing to confirm whether they are new coronaviruses. The steps of nucleic acid detection are mainly divided into three steps: […]
Nucleic acid extraction is used in molecular biochemical tests and diagnosis, and is the first step of cloning, transformation, enzyme digestion, in vitro transcription, amplification, and sequencing. However, due to the large amount of proteins, carbohydrates, metabolites and other contaminants in the original sample, it is not easy to extract high-quality nucleic acids. It is […]
The nucleic acid extraction system is an instrument that uses matching nucleic acid extraction reagents to automatically complete sample nucleic acid extraction. The magnetic bead method is to lyse the cell tissue sample through the lysis solution, the nucleic acid molecules free from the sample are specifically adsorbed to the surface of the magnetic particles, […]
The so-called biomagnetic beads refer to superparamagnetic microspheres with fine particle size. Magnetic beads generally have super-strong paramagnetism and can quickly gather in a magnetic field, and after leaving the magnetic field, they can help to uniformly disperse the magnetic separation. Secondly, it has a suitable particle size with small difference to ensure a strong […]
Nucleic acid is the carrier of genetic information, the most important biological information molecule, and the main object of molecular biology research. Therefore, nucleic acid extraction is the most important and basic operation in molecular biology experimental technology. Nucleic acid is divided into deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). RNA can be divided into […]
As of 0:00 on January 23, a total of 571 cases of novel coronavirus pneumonia have been confirmed in my country, and 17 cases have died. Changes in the pneumonia epidemic caused by new coronavirus infection in Wuhan Date Cumulative confirmed cases Cumulative cured and discharged Treating severe illness Cumulative deaths 1.14 41 7 6 […]
A new study published in the journal Nature found that there is an association between cerebral palsy and genetic variation. This surprising discovery challenges the claim that environmental factors are the only cause of cerebral palsy. According to study co-author Stephen Scherer, many people were not optimistic about this study at first, because for many […]
A reporter from the Beijing News noted that BGI has raised funds several times in the past two years, with more than 40 institutional shareholders behind it. The prospectus shows that before going public, BGI has mainly experienced three rounds of financing: in 2012 for BGI Technology, BGI Medical in 2014, and 2015 after the […]
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