Advantages and uses of common magnetic beads
High-quality magnetic beads have the characteristics of uniform size distribution, high surface loading, extremely short magnetic response time, high dispersion stability, etc., which can quickly and efficiently separate the test object from the sample, greatly improving the detection efficiency. In addition, there are many types of magnetic beads, and different magnetic beads have different advantages and different uses. Next, the editor of Aisen will share with you the relevant knowledge about the advantages and uses of common magnetic beads.
Advantages and uses of carboxyl magnetic beads
1. Advantages
(1) It can be coupled with biomolecules such as protein, nucleic acid, streptavidin, polypeptide, enzyme, etc. through the activation of EDCNHS;
(2) 1μm in size, uniform size, granular roughness on the surface, high specific surface area, extremely high carboxyl loading capacity, and low non-specific adsorption capacity;
(3) It has superparamagnetism, fast magnetic response speed, good monodispersity, and can ensure the uniformity of the reaction and the consistency of detection;
(4) It has a highly hydrophilic surface and good biocompatibility;
(5) Excellent suspension, slow semi-sedimentation speed, suitable for automatic operation.
2. Purpose
Chemiluminescence, gene capture, protein purification, cell sorting.
Advantages and uses of streptavidin magnetic beads
1. Advantages
(1) It can be used for the coupling of biotinylated proteins, nucleic acids, polysaccharides, lipids, enzymes and other biomolecules immediately;
(2) 1μm in size, uniform size, granular roughness on the surface, high specific surface area, extremely high streptavidin loading and biotinylated protein/nucleic acid coupling rate;
(3) Surface modification of hydrophilic polymer molecules and covalent coupling of multi-layer streptavidin. Streptavidin is densely adsorbed on the surface with few exposed sites on the surface, which greatly reduces non-specific adsorption ；
(4) It has good suspension and is stable within pH (3.0-9.0), and can be used for automated high-throughput experimental operations.
2. Purpose
Chemiluminescence, protein and nucleic acid separation.
Advantages and uses of amino magnetic beads
1. Advantages
(1) It can be coupled with biological molecules such as proteins, nucleic acids, polysaccharides, lipids, enzymes, etc. through a variety of coupling methods;
(2) 1μm in size, uniform size, granular roughness on the surface, high specific surface area, and extremely high amino loading;
(3) It has superparamagnetism, fast magnetic response speed, good monodispersity, and can ensure the uniformity of the reaction and the consistency of detection;
(4) It has a highly hydrophilic surface and good biocompatibility;
(5) Excellent suspension, slow semi-sedimentation speed, suitable for automatic operation.
2. Purpose
Chemiluminescence, cell, virus, nucleic acid, antibody separation and purification.
The above is the introduction of the advantages and uses of common magnetic beads. Different magnetic beads have different advantages and performances, and their uses are also different. The suitable magnetic beads should be selected according to their performance characteristics. The magnetic beads produced by Aisen Biotechnology are rich in varieties and excellent in performance. Customers in need are welcome to call for consultation.
