Magnetic Beads
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Nucleic Acid Extraction Silicon-based Magnetic Beads
Nucleic Acid Extraction Carboxyl Magnetic Beads
The surface of nano-scale magnetic beads is modified with specific active functional groups that can adsorb nucleic acids. By using different lysing solutions, binding solutions, and washing solutions, they can specifically bind to the target nucleic acid under specific conditions, while using magnetic beads With its own magnetism, it can easily achieve directional movement and enrichment under the action of an external magnetic field, so as to achieve the purpose of separating nucleic acid and impurities, and then achieve the separation and purification of target substances to obtain purified nucleic acid.
The magnetic bead method does not require centrifugation, is simple to operate, and is suitable for automated extraction. The entire extraction process takes a short time. At present, most nucleic acid extractors on the market use magnetic bead separation to achieve automation.
Silicon-based magnetic beads/carboxyl magnetic beads, streptavidin magnetic beads, chemiluminescent magnetic beads
Application: antibody purification, molecular separation, cell detection, microbial separation, chemiluminescence, etc.
High throughput automation
Simple operation and high efficiency
Safe and non-toxic
Good purity and high yield
High sensitivity
Fluorescence PCR verifies the difference between column method and magnetic bead method for nucleic acid extraction
Sample information | Column extraction CT value | Magnetic beads extract CT value |
Spleen | 20.36 | 19.5 |
Lung | 22.49 | 20.29 |
Kidney | 25.04 | 25.33 |
Lymph | 24.06 | 24.22 |
Blank control | N/A | N/A |
Positive control | 22.37 | 22.26 |
Negative control | N/A | N/A |
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